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DPYSL5 Antibody (monoclonal) (M02)
Mouse monoclonal antibody raised against a partial recombinant DPYSL5.
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | Q9BPU6 |
| Other Accession | NM_020134 |
| Reactivity | Human |
| Host | mouse |
| Clonality | Monoclonal |
| Isotype | IgG2b Kappa |
| Clone Names | 2G4 |
| Calculated MW | 61421 Da |
| Gene ID | 56896 |
|---|---|
| Other Names | Dihydropyrimidinase-related protein 5, DRP-5, CRMP3-associated molecule, CRAM, Collapsin response mediator protein 5, CRMP-5, UNC33-like phosphoprotein 6, ULIP-6, DPYSL5, CRMP5, ULIP6 |
| Target/Specificity | DPYSL5 (NP_064519, 466 a.a. ~ 564 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa. |
| Dilution | WB~~1:500~1000 |
| Format | Clear, colorless solution in phosphate buffered saline, pH 7.2 . |
| Storage | Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing. |
| Precautions | DPYSL5 Antibody (monoclonal) (M02) is for research use only and not for use in diagnostic or therapeutic procedures. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Members of the CRMP family, such as DPYSL5, are believed to play a role in growth cone guidance during neural development.
References
Onco-neural antibodies and tumour type determine survival and neurological symptoms in paraneoplastic neurological syndromes with Hu or CV2/CRMP5 antibodies. Honnorat J, et al. J Neurol Neurosurg Psychiatry, 2009 Apr. PMID 18931014.Extensive expression of collapsin response mediator protein 5 (CRMP5) is a specific marker of high-grade lung neuroendocrine carcinoma. Meyronet D, et al. Am J Surg Pathol, 2008 Nov. PMID 18769332.High-titer collapsin response-mediating protein-associated (CRMP-5) paraneoplastic optic neuropathy and Vitritis as the only clinical manifestations in a patient with small cell lung carcinoma. Margolin E, et al. J Neuroophthalmol, 2008 Mar. PMID 18347453.Autoimmune myelopathy associated with collapsin response-mediator protein-5 immunoglobulin G. Keegan BM, et al. Ann Neurol, 2008 Apr. PMID 18306241.A human protein-protein interaction network: a resource for annotating the proteome. Stelzl U, et al. Cell, 2005 Sep 23. PMID 16169070.
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