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>   home   >   Products   >   Primary Antibodies   >   Signal Transduction   >   KRT18 Antibody (monoclonal) (M01)   

KRT18 Antibody (monoclonal) (M01)

Mouse monoclonal antibody raised against a full length recombinant KRT18.

  • WB - KRT18 Antibody (monoclonal) (M01) AT2655a
    Antibody Reactive Against Recombinant Protein.Western Blot detection against Immunogen (47.41 KDa) .
  • WB - KRT18 Antibody (monoclonal) (M01) AT2655a
    KRT18 monoclonal antibody (M01), clone 2F8 Western Blot analysis of KRT18 expression in HeLa ( (Cat # AT2655a )
  • WB - KRT18 Antibody (monoclonal) (M01) AT2655a
    Western Blot analysis of KRT18 expression in transfected 293T cell line by KRT18 monoclonal antibody (M01), clone 2F8.

    Lane 1: KRT18 transfected lysate(48.1 KDa).
    Lane 2: Non-transfected lysate.
  • IHC - KRT18 Antibody (monoclonal) (M01) AT2655a
    Immunoperoxidase of monoclonal antibody to KRT18 on formalin-fixed paraffin-embedded human liver tissue. [antibody concentration 3 ug/ml]
  • IF - KRT18 Antibody (monoclonal) (M01) AT2655a
    Immunofluorescence of monoclonal antibody to KRT18 on HeLa cell. [antibody concentration 10 ug/ml]
  • IP - KRT18 Antibody (monoclonal) (M01) AT2655a
    Immunoprecipitation of KRT18 transfected lysate using anti-KRT18 monoclonal antibody and Protein A Magnetic Bead (U0007), and immunoblotted with KRT18 MaxPab rabbit polyclonal antibody.
  • E - KRT18 Antibody (monoclonal) (M01) AT2655a
    Detection limit for recombinant GST tagged KRT18 is approximately 0.1ng/ml as a capture antibody.
Product Information
  • Applications Legend:
  • WB=Western Blot
  • IHC=Immunohistochemistry
  • IHC-P=Immunohistochemistry (Paraffin-embedded Sections)
  • IHC-F=Immunohistochemistry (Frozen Sections)
  • IF=Immunofluorescence
  • FC=Flow Cytopmetry
  • IC=Immunochemistry
  • ICC=Immunocytochemistry
  • IP=Immunoprecipitation
  • DB=Dot Blot
  • CHIP=Chromatin Immunoprecipitation
  • FA=Fluorescence Assay
  • IEM=Immunoelectronmicroscopy
  • EIA=Enzyme Immunoassay
Primary Accession P05783
Other Accession BC000180
Reactivity Human
Host Mouse
Clonality Monoclonal
Isotype IgG2a Kappa
Clone Names 2F8
Calculated MW 48058 Da
Additional Information
Gene ID 3875
Other Names Keratin, type I cytoskeletal 18, Cell proliferation-inducing gene 46 protein, Cytokeratin-18, CK-18, Keratin-18, K18, KRT18, CYK18
Target/Specificity KRT18 (AAH00180, 1 a.a. ~ 430 a.a) full-length recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
Dilution WB~~1:500~1000
Format Clear, colorless solution in phosphate buffered saline, pH 7.2 .
StorageStore at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
PrecautionsKRT18 Antibody (monoclonal) (M01) is for research use only and not for use in diagnostic or therapeutic procedures.
Research Areas
Citations ( 0 )


KRT18 encodes the type I intermediate filament chain keratin 18. Keratin 18, together with its filament partner keratin 8, are perhaps the most commonly found members of the intermediate filament gene family. They are expressed in single layer epithelial tissues of the body. Mutations in this gene have been linked to cryptogenic cirrhosis. Two transcript variants encoding the same protein have been found for this gene.


Ectopic coexpression of keratin 8 and 18 promotes invasion of transformed keratinocytes and is induced in patients with cutaneous squamous cell carcinoma. Yamashiro Y, et al. Biochem Biophys Res Commun, 2010 Aug 27. PMID 20659422. Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia. Jugessur A, et al. PLoS One, 2010 Jul 9. PMID 20634891. Keratin variants predispose to acute liver failure and adverse outcome: race and ethnic associations. Strnad P, et al. Gastroenterology, 2010 Sep. PMID 20538000. Significant high expression of cytokeratins 7, 8, 18, 19 in pulmonary large cell neuroendocrine carcinomas, compared to small cell lung carcinomas. Nagashio R, et al. Pathol Int, 2010 Feb. PMID 20398190. Relationship between serum concentrations of keratin-18 and apoptosis in chronic hepatitis C. Gonzalez-Quintela A, et al. Clin Chem Lab Med, 2010 Jun. PMID 20374042.

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$ 350.00
Cat# AT2655a
Availability: 7-10 days
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