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Zebrafish SIM1 Antibody (N-term)
Affinity Purified Rabbit Polyclonal Antibody (Pab)
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Application 
| WB, E |
|---|---|
| Primary Accession | F1QMF7 |
| Other Accession | P05709, Q61045, P81133 |
| Reactivity | Zebrafish |
| Predicted | Human, Mouse, Drosophila |
| Host | Rabbit |
| Clonality | Polyclonal |
| Isotype | Rabbit IgG |
| Clone/Animal Names | RB32160 |
| Calculated MW | 82919 Da |
| Antigen Region | 1-30 aa |
| Gene ID | 260351 |
|---|---|
| Other Names | Single-minded homolog 1;SIM1;BHLHE14;sim1a;Single-minded homolog 1-A |
| Target/Specificity | This Zebrafish SIM1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of Zebrafish SIM1. |
| Dilution | WB~~1:1000 |
| Format | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
| Storage | Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles. |
| Precautions | Zebrafish SIM1 Antibody (N-term) is for research use only and not for use in diagnostic or therapeutic procedures. |
| Name | F1QMF7 |
|---|
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Provided below are standard protocols that you may find useful for product applications.
Background
SIM1 and SIM2 genes are Drosophila single-minded (sim) gene homologs. SIM1 transcript was detected only in fetal kidney out of various adult and fetal tissues tested. Since the sim gene plays an important role in Drosophila development and has peak levels of expression during the period of neurogenesis,it was proposed that the human SIM gene is a candidate for involvement in certain dysmorphic features (particularly the facial and skull characteristics), abnormalities of brain development, and/or mental retardation of Down syndrome.
References
Ghoussaini, M., et al. Obesity (Silver Spring) 18(8):1670-1675(2010) Tolson, K.P., et al. J. Neurosci. 30(10):3803-3812(2010) Traurig, M., et al. Diabetes 58(7):1682-1689(2009) Gregorio, S.P., et al. Psychiatry Res 165 (1-2), 1-9 (2009) : Hung, C.C., et al. Int J Obes (Lond) 31(3):429-434(2007)
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