Register or Login
  • All
  • Uniprot Id
  • Catalog #
  • Peptide Sequence
>   home   >   Products   >   Peptides   >   Blocking Peptides   >   GNE Antibody (N-term) Blocking peptide   

GNE Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9Y223
Clone Names 100311179
Peptide ID 100311179
Additional Information
Gene ID 10020
Other Names Bifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase, UDP-GlcNAc-2-epimerase/ManAc kinase, UDP-N-acetylglucosamine 2-epimerase (hydrolyzing), UDP-GlcNAc-2-epimerase, Uridine diphosphate-N-acetylglucosamine-2-epimerase, N-acetylmannosamine kinase, ManAc kinase, GNE, GLCNE
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GNE
Synonyms GLCNE
Function Regulates and initiates biosynthesis of N- acetylneuraminic acid (NeuAc), a precursor of sialic acids. Plays an essential role in early development (By similarity). Required for normal sialylation in hematopoietic cells. Sialylation is implicated in cell adhesion, signal transduction, tumorigenicity and metastatic behavior of malignant cells.
Cellular Location Cytoplasm.
Tissue Location Highest expression in liver and placenta. Also found in heart, brain, lung, kidney, skeletal muscle and pancreas Isoform 1 is expressed in heart, brain, kidney, liver, placenta, lung, spleen, pancreas, skeletal muscle and colon. Isoform 2 is expressed mainly in placenta, but also in brain, kidney, liver, lung, pancreas and colon. Isoform 3 is expressed at low level in kidney, liver, placenta and colon.
Research Areas
Citations (0)

Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.

Submit your citation using an Abcepta antibody to, and receive a free "I Love Antibodies" mug.


The protein encoded by this gene is a bifunctional enzymethat initiates and regulates the biosynthesis of N-acetylneuraminicacid (NeuAc), a precursor of sialic acids. It is a rate-limitingenzyme in the sialic acid biosynthetic pathway. Sialic acidmodification of cell surface molecules is crucial for theirfunction in many biologic processes, including cell adhesion andsignal transduction. Differential sialylation of cell surfacemolecules is also implicated in the tumorigenicity and metastaticbehavior of malignant cells. Mutations in this gene are associatedwith sialuria, autosomal recessive inclusion body myopathy, andNonaka myopathy. Alternative splicing of this gene results intranscript variants encoding different isoforms. [provided byRefSeq].


Stober, A., et al. Neuromuscul. Disord. 20(5):335-336(2010)Reinke, S.O., et al. Glycoconj. J. 26(4):415-422(2009)Tong, Y., et al. PLoS ONE 4 (10), E7165 (2009) :Reinke, S.O., et al. FEBS Lett. 581(17):3327-3331(2007)Watts, G.D., et al. Neuromuscul. Disord. 13 (7-8), 559-567 (2003) :

Abcepta welcomes feedback from its customers.

If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.

If you have any additional inquiries please email technical services at

Cat# BP12285a
Availability: Back Order
Bulk Size
Seasonal Special on Bulk Order
Request Quote Here

Ordering Information

United States
AlbaniaAustraliaAustriaBelgiumBosnia & HerzegovinaBrazilBulgariaCanadaCentral AmericaChinaCroatiaCyprusCzech RepublicDenmarkEstoniaFinlandFranceGermanyGreeceHong KongHungaryIcelandIndiaIndonesiaIrelandIsraelItalyJapanLatviaLithuaniaLuxembourgMacedoniaMalaysiaMaltaNetherlandsNew ZealandNorwayPakistanPolandPortugalRomaniaSerbiaSingaporeSlovakiaSloveniaSouth AfricaSouth KoreaSpainSwedenSwitzerlandTaiwanTurkeyUnited KingdomUnited StatesVietnamWorldwideOthers
Abcepta, Inc.
(888) 735-7227 / (858) 622-0099
(858) 622-0609
USA Headquarters
(888) 735-7227 / (858) 622-0099 or (858) 875-1900

Shipping Information

Domestic orders (in stock items)
Shipped out the same day. Orders placed after 1 PM (PST) will ship out the next business day.
International orders
Contact your local distributors
Terms & Conditions