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POMT1 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q9Y6A1
Clone Names 100318194
Peptide ID 100318194
Additional Information
Gene ID 10585
Other Names Protein O-mannosyl-transferase 1, Dolichyl-phosphate-mannose--protein mannosyltransferase 1, POMT1
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name POMT1
Function Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. Coexpression of both POMT1 and POMT2 is necessary for enzyme activity, expression of either POMT1 or POMT2 alone is insufficient (PubMed:12369018, PubMed:14699049, PubMed:28512129). Essentially dedicated to O-mannosylation of alpha-DAG1 and few other proteins but not of cadherins and protocaherins (PubMed:28512129).
Cellular Location Endoplasmic reticulum membrane; Multi-pass membrane protein
Tissue Location Widely expressed. Highly expressed in testis, heart and pancreas. Detected at lower levels in kidney, skeletal muscle, brain, placenta, lung and liver
Research Areas
Citations (0)

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The protein encoded by this gene is anO-mannosyltransferase that requires interaction with the product ofthe POMT2 gene for enzymatic function. The encoded protein is foundin the membrane of the endoplasmic reticulum. Defects in this geneare a cause of Walker-Warburg syndrome (WWS) and limb-girdlemuscular dystrophy type 2K (LGMD2K). Several transcript variantsencoding different isoforms have been found for this gene.


Manya, H., et al. J. Biochem. 147(3):337-344(2010)Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :Cotarelo, R.P., et al. Clin. Genet. 76(1):108-112(2009)Mercuri, E., et al. Neurology 72(21):1802-1809(2009)Judas, M., et al. Neuropediatrics 40(1):6-14(2009)

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Cat# BP12380b
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