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SNRPB2 Antibody (N-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P08579
Clone Names 100318196
Peptide ID 100318196
Additional Information
Gene ID 6629
Other Names U2 small nuclear ribonucleoprotein B'', U2 snRNP B'', SNRPB2
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SNRPB2
Function Involved in pre-mRNA splicing as component of the spliceosome (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346). Associated with sn-RNP U2, where it contributes to the binding of stem loop IV of U2 snRNA (PubMed:9716128).
Cellular Location Nucleus
Research Areas
Citations (0)

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Background

The protein encoded by this gene associates with stem loopIV of U2 small nuclear ribonucleoprotein (U2 snRNP) in the presenceof snRNP-A'. The encoded protein may play a role in pre-mRNAsplicing. Autoantibodies from patients with systemic lupuserythematosus frequently recognize epitopes on the encoded protein.Two transcript variants encoding the same protein have been foundfor this gene.

References

Oh, J.H., et al. Mamm. Genome 16(12):942-954(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Chung, S., et al. Biochim. Biophys. Acta 1576(3):287-297(2002)Jurica, M.S., et al. RNA 8(4):426-439(2002)

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Cat# BP12381a
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