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HSD17B4 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession P51659
Clone Names 100311212
Peptide ID 100311212
Additional Information
Gene ID 3295
Other Names Peroxisomal multifunctional enzyme type 2, MFE-2, 17-beta-hydroxysteroid dehydrogenase 4, 17-beta-HSD 4, D-bifunctional protein, DBP, Multifunctional protein 2, MPF-2, (3R)-hydroxyacyl-CoA dehydrogenase, 111n12, Enoyl-CoA hydratase 2, 3-alpha, 7-alpha, 12-alpha-trihydroxy-5-beta-cholest-24-enoyl-CoA hydratase, HSD17B4, EDH17B4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name HSD17B4
Synonyms EDH17B4, SDR8C1
Function Bifunctional enzyme acting on the peroxisomal beta- oxidation pathway for fatty acids. Catalyzes the formation of 3- ketoacyl-CoA intermediates from both straight-chain and 2-methyl- branched-chain fatty acids.
Cellular Location Peroxisome.
Tissue Location Present in many tissues with highest concentrations in liver, heart, prostate and testis
Research Areas
Citations (0)

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The protein encoded by this gene is a bifunctional enzymethat is involved in the peroxisomal beta-oxidation pathway forfatty acids. It also acts as a catalyst for the formation of3-ketoacyl-CoA intermediates from both straight-chain and2-methyl-branched-chain fatty acids. Defects in this gene thataffect the peroxisomal fatty acid beta-oxidation activity are acause of D-bifunctional protein deficiency (DBPD). An apparentpseudogene of this gene is present on chromosome 8. [provided byRefSeq].


Canzian, F., et al. Hum. Mol. Genet. 19(19):3873-3884(2010)Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010)Kashiwayama, Y., et al. J. Biol. Chem. 285(34):26315-26325(2010)Pierce, S.B., et al. Am. J. Hum. Genet. 87(2):282-288(2010)Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010)

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Cat# BP12516c
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