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UGCG Antibody (N-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q16739
Clone Names 100318200
Peptide ID 100318200
Additional Information
Gene ID 7357
Other Names Ceramide glucosyltransferase, GLCT-1, Glucosylceramide synthase, GCS, UDP-glucose ceramide glucosyltransferase, UDP-glucose:N-acylsphingosine D-glucosyltransferase, UGCG
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the first glycosylation step in glycosphingolipid biosynthesis, the transfer of glucose to ceramide. May also serve as a "flippase".
Cellular Location Golgi apparatus membrane; Multi-pass membrane protein
Tissue Location Found in all tissues examined.
Research Areas
Citations (0)

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Glycosphingolipids (GSLs) are a group of membranecomponents that contain lipid and sugar moieties. They are presentin essentially all animal cells and are believed to have importantroles in various cellular processes. UDP-glucose ceramideglucosyltransferase catalyzes the first glycosylation step inglycosphingolipid biosynthesis. The product, glucosylceramide, isthe core structure of more than 300 GSLs. UGCG is widely expressedand transcription is upregulated during keratinocytedifferentiation.


Yang, G.Q., et al. Zhonghua Yi Xue Yi Chuan Xue Za Zhi 27(3):299-304(2010)Ruckhaberle, E., et al. J. Cancer Res. Clin. Oncol. 135(1):81-90(2009)Xie, P., et al. Leuk. Res. 32(3):475-480(2008)Marks, N., et al. Brain Res. 1191, 136-147 (2008) :Fazi, B., et al. Biochem. Biophys. Res. Commun. 342(3):881-886(2006)

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Cat# BP12616a
Availability: Back Order
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