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TRUB1 Antibody (Center) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q8WWH5
Clone Names 91201302
Peptide ID 91201302
Additional Information
Gene ID 142940
Other Names Probable tRNA pseudouridine synthase 1, 5499-, TRUB1, PUS4
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TRUB1 {ECO:0000303|PubMed:12736709, ECO:0000312|HGNC:HGNC:16060}
Function Pseudouridine synthase that catalyzes pseudouridylation of mRNAs (PubMed:28073919). Mediates pseudouridylation of mRNAs with the consensus sequence 5'-GUUCNANNC-3', harboring a stem-loop structure (PubMed:28073919). Constitutes the major pseudouridine synthase acting on mRNAs (PubMed:28073919).
Cellular Location Nucleus. Cytoplasm, cytosol. Note=Catalyzes pseudouridylation of mRNAs in the nucleus
Tissue Location Highly expressed in heart, skeletal muscle and liver. Expressed at lower levels in lung, small intestine, kidney and spleen.
Research Areas
Citations (0)

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Pseudouridine is an abundant component of rRNAs and tRNAsand is enzymatically generated by isomerization of uridine bypseudouridine synthase (Zucchini et al., 2003 [PubMed12736709]).


Grupe, A., et al. Am. J. Hum. Genet. 78(1):78-88(2006)Deloukas, P., et al. Nature 429(6990):375-381(2004)Zucchini, C., et al. Int. J. Mol. Med. 11(6):697-704(2003)

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Cat# BP12789c
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