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RNF38 Antibody (N-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H0F5 |
|---|---|
| Clone Names | 100324250 |
| Gene ID | 152006 |
|---|---|
| Other Names | E3 ubiquitin-protein ligase RNF38, 632-, RING finger protein 38, RNF38 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | RNF38 (HGNC:18052) |
|---|---|
| Function | Acts as an E3 ubiquitin-protein ligase able to ubiquitinate p53/TP53 which promotes its relocalization to discrete foci associated with PML nuclear bodies. Exhibits preference for UBE2D2 as a E2 enzyme. |
| Cellular Location | Nucleus. |
| Tissue Location | Widely expressed with highest levels in testis. |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Background
This gene encodes a protein with a coiled-coil motif and aRING-H2 motif (C3H2C2) at its carboxy-terminus. The RING motif is azinc-binding domain found in a large set of proteins playing rolesin diverse cellular processes including oncogenesis, development,signal transduction, and apoptosis. Multiple transcript variantsencoding different isoforms have been found for this gene.
References
Humphray, S.J., et al. Nature 429(6990):369-374(2004)Eisenberg, I., et al. Biochem. Biophys. Res. Commun. 294(5):1169-1176(2002)
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