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STX3 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q13277 |
|---|---|
| Clone Names | 80612063 |
| Gene ID | 6809 |
|---|---|
| Other Names | Syntaxin-3, STX3, STX3A |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | STX3 |
|---|---|
| Synonyms | STX3A |
| Function | Potentially involved in docking of synaptic vesicles at presynaptic active zones. Apical receptor involved in membrane fusion of apical vesicles. |
| Cellular Location | [Isoform A]: Apical cell membrane; Single-pass type IV membrane protein. Note=Localized to the inner and outer plexiform layers, the cell body and the inner segments of photoreceptors {ECO:0000250|UniProtKB:Q64704} |
| Tissue Location | [Isoform A]: Expressed in small intestine, kidney, pancreas, placenta as well as in retina. Weaker expression in lung, liver and heart. Not expressed in brain and skeletal muscle [Isoform 3]: Ubiquitously expressed. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The gene is a member of the syntaxin family. The encodedprotein is targeted to the apical membrane of epithelial cellswhere it forms clusters and is important in establishing andmaintaining polarity necessary for protein trafficking involvingvesicle fusion and exocytosis. Alternative splicing results inmultiple transcript variants.
References
Peng, R.W., et al. Biochem. J. 431(3):353-361(2010)Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Lee, B.Y., et al. Mol. Cell Proteomics 9(1):32-53(2010)Mistry, A.C., et al. Am. J. Physiol. Renal Physiol. 297 (2), F292-F300 (2009) :Low, S.H., et al. Mol. Biol. Cell 17(2):977-989(2006)
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