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C1orf71 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q6PJW8
Clone Names 100405210
Peptide ID 100405210
Additional Information
Gene ID 163882
Other Names Consortin, CNST, C1orf71
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms C1orf71
Function Required for targeting of connexins to the plasma membrane.
Cellular Location Cell membrane; Single-pass membrane protein. Golgi apparatus, trans-Golgi network membrane; Single-pass membrane protein. Cytoplasmic vesicle, secretory vesicle. Note=Located predominantly in the trans-Golgi network. Probably trafficks between the trans- Golgi network and the cell membrane via the secretory pathway
Research Areas
Citations (0)

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Targeting of numerous transmembrane proteins to the cellsurface is thought to depend on their recognition by cargoreceptors that interact with the adaptor machinery for anterogradetraffic at the distal end of the Golgi complex. Consortin (CNST) isan integral membrane protein that acts as a binding partner ofconnexins, the building blocks of gap junctions, and acts as atrans-Golgi network (TGN) receptor involved in connexin targetingto the plasma membrane and recycling from the cell surface (delCastillo et al., 2010 [PubMed 19864490]).


del Castillo, F.J., et al. Hum. Mol. Genet. 19(2):262-275(2010)Simpson, J.C., et al. EMBO Rep. 1(3):287-292(2000)

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Cat# BP13000b
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