|Other Names||Semaphorin-4C, SEMA4C, KIAA1739, SEMAI|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Cell surface receptor for PLXNB2 that plays an important role in cell-cell signaling. PLXNB2 binding promotes downstream activation of RHOA and phosphorylation of ERBB2 at 'Tyr-1248'. Required for normal brain development, axon guidance and cell migration (By similarity). Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.|
|Cellular Location||Cell junction, synapse, postsynaptic cell membrane, postsynaptic density; Single-pass type I membrane protein. Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Single-pass type I membrane protein|
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
Probable signaling receptor which may play a role in myogenic differentiation through activation of the stress-activated MAPK cascade.
Wu, H., et al. Eur. J. Cell Biol. 86(6):331-344(2007)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Inagaki, S., et al. J. Biol. Chem. 276(12):9174-9181(2001)Ohoka, Y., et al. Biochem. Biophys. Res. Commun. 280(1):237-243(2001)Wang, L.H., et al. J. Biol. Chem. 274(20):14137-14146(1999)
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