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C21orf59 Antibody (C-term) Blocking peptide

Synthetic peptide

     
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Product Information
Primary Accession P57076
Clone Names 100406030
Peptide ID 100406030
Additional Information
Gene ID 56683
Other Names UPF0769 protein C21orf59, C21orf59, C21orf48
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name CFAP298 (HGNC:1301)
Function Plays a role in motile cilium function, possibly by acting on outer dynein arm assembly (PubMed:24094744). Seems to be important for initiation rather than maintenance of cilium motility (By similarity). Required for correct positioning of the cilium at the apical cell surface, suggesting an additional role in the planar cell polarity (PCP) pathway (By similarity). May suppress canonical Wnt signaling activity (By similarity).
Cellular Location Cytoplasm. Cytoplasm, cytoskeleton, cilium basal body {ECO:0000250|UniProtKB:A0A1L8HCK2}. Note=Partially colocalized with SASS6 in cytoplasmic puncta, suggesting a centrosomal localization. {ECO:0000250|UniProtKB:Q5U3Z0}
Research Areas
Citations (0)

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Background

The function of the C21orf59 protein remains unknown.

References

Denoeud, F., et al. Genome Res. 17(6):746-759(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)Rush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)

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Cat# BP13024b
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