|Other Names||CXADR-like membrane protein, Adipocyte adhesion molecule, Coxsackie- and adenovirus receptor-like membrane protein, CAR-like membrane protein, CLMP, ACAM, ASAM|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||May be involved in the cell-cell adhesion. May play a role in adipocyte differentiation and development of obesity. Is required for normal small intestine development.|
|Cellular Location||Cell junction, tight junction. Cell membrane; Single-pass type I membrane protein|
|Tissue Location||Predominantly expressed in epithelial cells within different tissues and in the white adipose tissue Expressed at high levels in small intestine and placenta, at intermediate levels in the heart, skeletal muscle, colon, spleen, kidney and lung and at low levels in the liver and peripheral blood leukocytes. Highly abundant in the intestine during embryo and fetal development (at protein level)|
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Provided below are standard protocols that you may find useful for product applications.
The CTX (see VSIG2, MIM 606011) family of proteins,including ASAM, are type I transmembrane proteins within the Igsuperfamily that localize to junctional complexes betweenendothelial and epithelial cells and may play a role in cell-celladhesion (Raschperger et al., 2004 [PubMed 14573622]).[supplied byOMIM].
Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) :Kawabata, K., et al. Gene Ther. 14(16):1199-1207(2007)Lamesch, P., et al. Genomics 89(3):307-315(2007)Eguchi, J., et al. Biochem. J. 387 (PT 2), 343-353 (2005) :Raschperger, E., et al. J. Biol. Chem. 279(1):796-804(2004)
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