SPT19 Antibody (C-term) Blocking peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q7Z5L4 |
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Clone Names | 91119264 |
Gene ID | 219938 |
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Other Names | Spermatogenesis-associated protein 19, mitochondrial, Spermatogenic cell-specific gene 1 protein, Spergen-1, SPATA19, SPERGEN1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP13095b was selected from the C-term region of SPT19. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | SPATA19 |
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Synonyms | SPERGEN1 |
Function | Essential for sperm motility and male fertility (By similarity). Plays an important role in sperm motility by regulating the organization and function of the mitochondria and is also required for correct sperm midpiece assembly (By similarity). |
Cellular Location | Mitochondrion outer membrane {ECO:0000250|UniProtKB:Q9DAQ9}. Mitochondrion {ECO:0000250|UniProtKB:Q9DAQ9}. Cell projection, cilium, flagellum {ECO:0000250|UniProtKB:Q9DAQ9}. Note=Localizes to the midpiece of the sperm flagellum. {ECO:0000250|UniProtKB:Q9DAQ9} |
Tissue Location | Expressed specifically in testis. |
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Provided below are standard protocols that you may find useful for product applications.
Background
SPT19 may have a role in spermiogenesis.
References
Ghafouri-Fard, S., et al. Br. J. Dermatol. 162(4):772-779(2010)Stolk, L., et al. Nat. Genet. 41(6):645-647(2009)Lamesch, P., et al. Genomics 89(3):307-315(2007)Olsen, J.V., et al. Cell 127(3):635-648(2006)Olsen, J.V., et al. Cell 127(3):635-648(2006)
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