|Other Names||Sodium/hydrogen exchanger 5, Na(+)/H(+) exchanger 5, NHE-5, Solute carrier family 9 member 5, SLC9A5, NHE5|
|Target/Specificity||The synthetic peptide sequence used to generate the antibody AP13149b was selected from the C-term region of SLC9A5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction (By similarity).|
|Cellular Location||Membrane; Multi-pass membrane protein.|
|Tissue Location||Expressed in brain, testis, spleen, and skeletal muscle|
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Provided below are standard protocols that you may find useful for product applications.
SLC9A5 is involved in pH regulation to eliminate acids generated by active metabolism or to counter adverse environmental conditions. Major proton extruding system driven by the inward sodium ion chemical gradient. Plays an important role in signal transduction (By similarity).
Diering, G.H., et al. J. Biol. Chem. 284(20):13892-13903(2009)Onishi, I., et al. Cell. Signal. 19(1):194-203(2007)Szabo, E.Z., et al. Proc. Natl. Acad. Sci. U.S.A. 102(8):2790-2795(2005)Lin, W.M., et al. Sheng Li Xue Bao 55(1):79-82(2003)Inoue, H., et al. Biol. Pharm. Bull. 26(2):148-155(2003)
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