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XPNPEP3 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9NQH7
Clone Names 100406206
Peptide ID 100406206
Additional Information
Gene ID 63929
Other Names Probable Xaa-Pro aminopeptidase 3, X-Pro aminopeptidase 3, Aminopeptidase P3, APP3, XPNPEP3
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13203b was selected from the C-term region of XPNPEP3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Catalyzes the removal of a penultimate prolyl residue from the N-termini of peptides, such as Leu-Pro-Ala (PubMed:25609706, PubMed:28476889). Also shows low activity towards peptides with Ala or Ser at the P1 position (PubMed:28476889).
Cellular Location Isoform 1: Mitochondrion Cytoplasm. Note=Mainly mitochondrial. Translocates to the cytoplasm following TNFRSF1B activation.
Tissue Location Isoform 1 and isoform 2 are widely expressed, with isoform 1 being more abundant.
Research Areas
Citations (0)

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XPNPEP3 belongs to a family of X-pro-aminopeptidases (EC3.4.11.9) that utilize a metal cofactor and remove the N-terminalamino acid from peptides with a proline residue in the penultimateposition (summary by Ersahin et al., 2005 [PubMed15708373]).


O'Toole, J.F., et al. J. Clin. Invest. 120(3):791-802(2010)Ersahin, C., et al. Arch. Biochem. Biophys. 435(2):303-310(2005)Bouwmeester, T., et al. Nat. Cell Biol. 6(2):97-105(2004)Collins, J.E., et al. Genome Biol. 5 (10), R84 (2004) :Dunham, I., et al. Nature 402(6761):489-495(1999)

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Cat# BP13203b
Availability: Back Order
Bulk Size
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