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SLC27A4 Antibody (C-term) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q6P1M0
Clone Names 100405053
Peptide ID 100405053
Additional Information
Gene ID 10999
Other Names Long-chain fatty acid transport protein 4, FATP-4, Fatty acid transport protein 4, 621-, Solute carrier family 27 member 4, SLC27A4, ACSVL4, FATP4
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13227b was selected from the C-term region of SLC27A4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC27A4
Synonyms ACSVL4, FATP4
Function Involved in translocation of long-chain fatty acids (LFCA) across the plasma membrane. Appears to be the principal fatty acid transporter in small intestinal enterocytes. Plays a role in the formation of the epidermal barrier. Required for fat absorption in early embryogenesis. Has acyl-CoA ligase activity for long-chain and very-long-chain fatty acids (VLCFAs). Indirectly inhibits RPE65 via substrate competition and via production of VLCFA derivatives like lignoceroyl-CoA. Prevents light-induced degeneration of rods and cones (By similarity).
Cellular Location Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane
Tissue Location Expressed at highest levels in brain, testis, colon and kidney. Expressed at medium levels in heart and liver, small intestine and stomach. Expressed at low levels in peripheral leukocytes, bone marrow, skeletal muscle and aorta. Expressed in adipose tissue.
Research Areas
Citations (0)

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This gene encodes a member of a family of fatty acidtransport proteins, which are involved in translocation oflong-chain fatty acids cross the plasma membrane. This protein isexpressed at high levels on the apical side of mature enterocytesin the small intestine, and appears to be the principal fatty acidtransporter in enterocytes. Clinical studies suggest this gene as acandidate gene for the insulin resistance syndrome. Mutations inthis gene have been associated with ichthyosis prematuritysyndrome.


Morice-Picard, F., et al. Am. J. Med. Genet. A 152A (10), 2664-2665 (2010) :Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010) :Ban, H.J., et al. BMC Genet. 11, 26 (2010) :Klar, J., et al. Am. J. Hum. Genet. 85(2):248-253(2009)Jia, Z., et al. J. Mol. Neurosci. 33(1):25-31(2007)

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Cat# BP13227b
Availability: Back Order
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