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SLC9A7 Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q96T83
Clone Names 100406282
Peptide ID 100406282
Additional Information
Gene ID 84679
Other Names Sodium/hydrogen exchanger 7, Na(+)/H(+) exchanger 7, NHE-7, Solute carrier family 9 member 7, SLC9A7, NHE7
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13243b was selected from the C-term region of SLC9A7. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name SLC9A7
Synonyms NHE7
Function Mediates electroneutral exchange of protons for Na(+) and K(+) across endomembranes. May contribute to Golgi volume and cation homeostasis.
Cellular Location Golgi apparatus, trans-Golgi network membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein
Tissue Location Ubiquitously expressed.
Research Areas
Citations (0)

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Organelles of the secretory and endocytic pathways aredistinguished by their luminal acidity, which is generated by theactivity of an electrogenic vacuolar-type hydrogen ATPase.Progressive acidification of vesicles in the endocytic pathway isessential for the redistribution and degradation of internalizedmembrane proteins, such as ligand receptor complexes andfluid-phase solutes. This gene is expressed predominantly in thetrans-Golgi network, and mediates the influx of sodium or potassiumin exchange for hydrogen. It may thus play an important role inmaintaining cation homeostasis and function of the trans-Golginetwork. This gene is part of a gene cluster on chromosome Xp11.23.


Fukura, N., et al. J. Membr. Biol. 234(3):149-158(2010)Kagami, T., et al. Mol. Membr. Biol. 25(5):436-447(2008)Lin, P.J., et al. J. Cell. Sci. 118 (PT 9), 1885-1897 (2005) :Ross, M.T., et al. Nature 434(7031):325-337(2005)Thiselton, D.L., et al. Genomics 79(4):560-572(2002)

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Cat# BP13243b
Availability: Back Order
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