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GRAMD1B Antibody (C-term) Blocking peptide

Synthetic peptide

Product Information
Primary Accession Q3KR37
Clone Names 100416172
Peptide ID 100416172
Additional Information
Gene ID 57476
Other Names GRAM domain-containing protein 1B, GRAMD1B, KIAA1201
Target/Specificity The synthetic peptide sequence used to generate the antibody AP13342b was selected from the C-term region of GRAMD1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Synonyms KIAA1201
Function Cholesterol transporter that mediates non-vesicular transport of cholesterol from the plasma membrane (PM) to the endoplasmic reticulum (ER) (By similarity). Contains unique domains for binding cholesterol and the PM, thereby serving as a molecular bridge for the transfer of cholesterol from the PM to the ER (By similarity). Plays a crucial role in cholesterol homeostasis in the adrenal gland and has the unique ability to localize to the PM based on the level of membrane cholesterol (By similarity). In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum-plasma membrane contact sites (EPCS) which is mediated by the GRAM domain (By similarity). At the EPCS, the sterol-binding VASt/ASTER domain binds to the cholesterol in the PM and facilitates its transfer from the PM to ER (By similarity).
Cellular Location Endoplasmic reticulum membrane; Single-pass membrane protein. Cell membrane; Single-pass membrane protein. Note=In lipid-poor conditions localizes to the ER membrane and in response to excess cholesterol in the PM is recruited to the endoplasmic reticulum- plasma membrane contact sites (EPCS)
Research Areas
Citations (0)

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The specific function of this protein remains unknown.


Slager, S.L., et al. Cancer Epidemiol. Biomarkers Prev. 19(4):1098-1102(2010)Di Bernardo, M.C., et al. Nat. Genet. 40(10):1204-1210(2008)Clark, H.F., et al. Genome Res. 13(10):2265-2270(2003)Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :

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Cat# BP13342b
Availability: Back Order
Bulk Size
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Ordering Information

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