KIR2DS4 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P43632 |
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Clone Names | 90723072 |
Gene ID | 3809 |
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Other Names | Killer cell immunoglobulin-like receptor 2DS4, CD158 antigen-like family member I, MHC class I NK cell receptor, Natural killer-associated transcript 8, NKAT-8, P58 natural killer cell receptor clones CL-39/CL-17, p58 NK receptor CL-39/CL-17, CD158i, KIR2DS4, CD158I, KKA3, NKAT8 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8581c was selected from the Center region of human KIR2DS4. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | KIR2DS4 {ECO:0000303|PubMed:24018270, ECO:0000312|HGNC:HGNC:6336} |
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Function | Receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells. |
Cellular Location | Cell membrane; Single-pass type I membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
KIR2DS4 is the receptor on natural killer (NK) cells for HLA-C alleles. Does not inhibit the activity of NK cells.
References
Campbell,K.S., et.al., Eur. J. Immunol. 28 (2), 599-609 (1998)Bottino,C., et.al., Eur. J. Immunol. 26 (8), 1816-1824 (1996)
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