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CARKD Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8IW45 |
|---|---|
| Clone Names | 90904011 |
| Gene ID | 55739 |
|---|---|
| Other Names | ATP-dependent (S)-NAD(P)H-hydrate dehydratase {ECO:0000255|HAMAP-Rule:MF_03157}, 42193 {ECO:0000255|HAMAP-Rule:MF_03157}, ATP-dependent NAD(P)HX dehydratase {ECO:0000255|HAMAP-Rule:MF_03157}, Carbohydrate kinase domain-containing protein {ECO:0000255|HAMAP-Rule:MF_03157}, CARKD {ECO:0000255|HAMAP-Rule:MF_03157} |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8700c was selected from the Center region of human CARKD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NAXD (HGNC:25576) |
|---|---|
| Function | Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ATP, which is converted to ADP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. |
| Cellular Location | Mitochondrion {ECO:0000255|HAMAP-Rule:MF_03157}. |
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Provided below are standard protocols that you may find useful for product applications.
Background
The exact function of CARKD remains unknown.
References
Kimura,K., et.al., Genome Res. 16 (1), 55-65 (2006)
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