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NEK10 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6ZWH5 |
|---|---|
| Clone Names | 90904152 |
| Gene ID | 152110 |
|---|---|
| Other Names | Serine/threonine-protein kinase Nek10, Never in mitosis A-related kinase 10, NimA-related protein kinase 10, NEK10 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8704c was selected from the Center region of human NEK10. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NEK10 (HGNC:18592) |
|---|---|
| Function | Plays a role in the cellular response to UV irradiation. Mediates G2/M cell cycle arrest, MEK autoactivation and ERK1/2- signaling pathway activation in response to UV irradiation. In ciliated cells of airways, it is involved in the regulation of mucociliary transport (PubMed:31959991). |
| Tissue Location | Expressed in the lung. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. NIMA subfamily.
References
Caenepeel,S., et.al., Proc. Natl. Acad. Sci. U.S.A. 101 (32), 11707-11712 (2004)
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