CCDC3 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q9BQI4 |
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Clone Names | 90909021 |
Gene ID | 83643 |
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Other Names | Coiled-coil domain-containing protein 3, Fat/vessel-derived secretory protein, Favine, CCDC3 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8744b was selected from the C-term region of human CCDC3. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CCDC3 |
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Function | Negatively regulates TNF-alpha-induced pro-inflammatory response in endothelial cells (ECs) via inhibition of TNF-alpha-induced NF-kappaB activation in ECs (PubMed:25193116). Positively regulates lipid accumulation in adipose cells (By similarity). |
Cellular Location | Secreted {ECO:0000250|UniProtKB:Q9D6Y1}. |
Tissue Location | Expressed in umbilical vein endothelial cells (HUVEC), and at lower levels in aortic smooth muscle cells (HASMC) |
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Provided below are standard protocols that you may find useful for product applications.
References
Mural,R.J., et.al., Submitted (05-JUL-2005) Celera Genomics, 45 W. Gude Dr., Rockville,MD 20850, USA
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