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FNDC5 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8NAU1 |
|---|---|
| Clone Names | 90909048 |
| Gene ID | 252995 |
|---|---|
| Other Names | Fibronectin type III domain-containing protein 5, Fibronectin type III repeat-containing protein 2, Irisin, FNDC5, FRCP2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8746b was selected from the C-term region of human FNDC5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | FNDC5 |
|---|---|
| Synonyms | FRCP2 |
| Function | [Irisin]: Mediates beneficial effects of muscular exercise. Induces browning of white adipose tissue by stimulating UCP1 expression, at least in part, via the nuclear receptor PPARA. |
| Cellular Location | [Fibronectin type III domain-containing protein 5]: Cell membrane; Single-pass membrane protein. Peroxisome membrane {ECO:0000250|UniProtKB:Q8K4Z2}; Single-pass membrane protein. Note=Imported into peroxisomes through the PEX5 receptor pathway. {ECO:0000250|UniProtKB:Q8K4Z2} |
| Tissue Location | Widely expressed, with highest levels in heart. Very low expression, if any, in colon, pancreas and spleen |
Research Areas
Citations (0)
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info@abcepta.com, and receive a free "I Love Antibodies" mug.
Application Protocols
Provided below are standard protocols that you may find useful for product applications.
References
Teufel,A., et.al., Gene 297 (1-2), 79-83 (2002)
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$ 277.78
Cat# BP8746b
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