CAN12 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q6ZSI9 |
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Clone Names | 80411162 |
Gene ID | 147968 |
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Other Names | Calpain-12, 3422-, Calcium-activated neutral proteinase 12, CANP 12, CAPN12 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP8838a was selected from the N-term region of human CAN12. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | CAPN12 |
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Function | Calcium-regulated non-lysosomal thiol-protease. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Calpains are a family of cytosolic calcium-activated cysteine proteases involved in a variety of cellular processes including apoptosis, cell division, modulation of integrin-cytoskeletal interactions, and synaptic plasticity (Dear et al., 2000 [PubMed 10964513]). CAPN12 belongs to the calpain large subunit family.[supplied by OMIM].
References
Dear,T.N., et.al., Genomics 68 (2), 152-160 (2000)
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