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EXOC5 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession O00471
Clone Names 90819032
Additional Information
Gene ID 10640
Other Names Exocyst complex component 5, Exocyst complex component Sec10, hSec10, EXOC5, SEC10, SEC10L1
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9006b was selected from the C-term region of human EXOC5. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name EXOC5
Synonyms SEC10, SEC10L1
Function Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane.
Cellular Location Cytoplasm. Midbody. Note=Localization at the midbody requires the presence of RALA, EXOC2 and EXOC3
Tissue Location Ubiquitous..
Research Areas
Citations (0)
citation

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Background

EXOC5 is a component of the exocyst complex, a multiple protein complex essential for targeting exocytic vesicles to specific docking sites on the plasma membrane. Though best characterized in yeast, the component proteins and functions of exocyst complex have been demonstrated to be highly conserved in higher eukaryotes. At least eight components of the exocyst complex, including this protein, are found to interact with the actin cytoskeletal remodeling and vesicle transport machinery. The complex is also essential for the biogenesis of epithelial cell surface polarity.

References

Kee,Y., et.al., Proc. Natl. Acad. Sci. U.S.A. 94 (26), 14438-14443 (1997)Hsu,S.C., et.al., Neuron 20 (6), 1111-1122 (1998)

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$ 277.78
Cat# BP9006b
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