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C11orf54 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9H0W9 |
|---|---|
| Clone Names | 90826102 |
| Gene ID | 28970 |
|---|---|
| Other Names | Ester hydrolase C11orf54, 31--, C11orf54 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9072b was selected from the C-term region of human C11orf54. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | C11orf54 |
|---|---|
| Function | Exhibits ester hydrolase activity on the substrate p- nitrophenyl acetate, in vitro (PubMed:16522806). Regulates DNA damage and repair by regulating HIF1A degradation via chaperone-mediated autophagy (CMA) (PubMed:37277441). |
| Cellular Location | Nucleus. Cytoplasm. Note=Mainly located in the cytoplasm |
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Provided below are standard protocols that you may find useful for product applications.
Background
C11orf54 exhibits ester hydrolase activity on the substrate p-nitrophenyl acetate.
References
Venkatesan,K., et.al. Nat. Methods 6 (1), 83-90 (2009)Wan,D., et.al., Proc. Natl. Acad. Sci. U.S.A. 101 (44), 15724-15729 (2004)
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