ACOT1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q86TX2 |
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Clone Names | 90909004 |
Gene ID | 641371 |
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Other Names | Acyl-coenzyme A thioesterase 1, Acyl-CoA thioesterase 1, CTE-I, CTE-Ib, Inducible cytosolic acyl-coenzyme A thioester hydrolase, Long chain acyl-CoA thioester hydrolase, Long chain acyl-CoA hydrolase, ACOT1, CTE1 |
Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9100a was selected from the N-term region of human ACOT1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | ACOT1 |
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Synonyms | CTE1 |
Function | Catalyzes the hydrolysis of acyl-CoAs into free fatty acids and coenzyme A (CoASH), regulating their respective intracellular levels. More active towards saturated and unsaturated long chain fatty acyl-CoAs (C12-C20). |
Cellular Location | Cytoplasm, cytosol. |
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Provided below are standard protocols that you may find useful for product applications.
Background
ACOT1 are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Active towards fatty acyl-CoA with chain-lengths of C12-C16 (By similarity).
References
Hunt,M.C., et.al., FASEB J. 20 (11), 1855-1864 (2006)Hunt,M.C., et.al., J. Lipid Res. 46 (9), 2029-2032 (2005)
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