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PHTF1 Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q9UMS5
Clone Names 90723099
Additional Information
Other Names Putative homeodomain transcription factor 1, PHTF1, PHTF
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9167c was selected from the Center region of human PHTF1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name PHTF1
Synonyms PHTF
Function May play a role in transcription regulation.
Cellular Location Nucleus.
Tissue Location Widely expressed with highest levels in testis. EMBL; AJ011863; CAB51572.1; -; mRNA EMBL; AL365321; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; AL133517; -; NOT_ANNOTATED_CDS; Genomic_DNA EMBL; BC002447; AAH02447.1; -; mRNA CCDS; CCDS81359.1; -. [Q9UMS5-2] CCDS; CCDS861.1; -. [Q9UMS5-1] RefSeq; NP_001309970.1; NM_001323041.1. [Q9UMS5-1] RefSeq; NP_001309971.1; NM_001323042.1. [Q9UMS5-1] RefSeq; NP_001309972.1; NM_001323043.1. [Q9UMS5-1] RefSeq; NP_001309976.1; NM_001323047.1. [Q9UMS5-2] RefSeq; NP_001309977.1; NM_001323048.1. [Q9UMS5-2] RefSeq; NP_001309978.1; NM_001323049.1. [Q9UMS5-2] RefSeq; NP_006599.2; NM_006608.2. [Q9UMS5-1] SMR; Q9UMS5; - BioGRID; 115968; 6 IntAct; Q9UMS5; 5 MINT; Q9UMS5; - STRING; 9606.ENSP00000358617; - iPTMnet; Q9UMS5; - PhosphoSitePlus; Q9UMS5; - BioMuta; PHTF1; - DMDM; 71152973; - EPD; Q9UMS5; - MassIVE; Q9UMS5; - PaxDb; Q9UMS5; - PeptideAtlas; Q9UMS5; - PRIDE; Q9UMS5; - ProteomicsDB; 85208; -. [Q9UMS5-1] ProteomicsDB; 85209; -. [Q9UMS5-2] Antibodypedia; 20143; 28 antibodies Ensembl; ENST00000357783; ENSP00000350428; ENSG00000116793. [Q9UMS5-2] Ensembl; ENST00000369604; ENSP00000358617; ENSG00000116793. [Q9UMS5-1] Ensembl; ENST00000393357; ENSP00000377025; ENSG00000116793. [Q9UMS5-1] GeneID; 10745; - KEGG; hsa:10745; - UCSC; uc001edn.4; human. [Q9UMS5-1] CTD; 10745; - DisGeNET; 10745; - EuPathDB; HostDB:ENSG00000116793.15; - GeneCards; PHTF1; - HGNC; HGNC:8939; PHTF1 HPA; ENSG00000116793; Low tissue specificity MIM; 604950; gene neXtProt; NX_Q9UMS5; - OpenTargets; ENSG00000116793; - PharmGKB; PA33278; - eggNOG; ENOG410IF1F; Eukaryota eggNOG; ENOG410ZM0V; LUCA GeneTree; ENSGT00390000011648; - InParanoid; Q9UMS5; - OMA; EAQTQMM; - OrthoDB; 710715at2759; - PhylomeDB; Q9UMS5; - TreeFam; TF323570; - BioGRID-ORCS; 10745; 1 hit in 790 CRISPR screens ChiTaRS; PHTF1; human GenomeRNAi; 10745; - Pharos; Q9UMS5; Tdark PRO; PR:Q9UMS5; - Proteomes; UP000005640; Chromosome 1 RNAct; Q9UMS5; protein Bgee; ENSG00000116793; Expressed in cerebellar hemisphere and 168 other tissues ExpressionAtlas; Q9UMS5; baseline and differential Genevisible; Q9UMS5; HS GO; GO:0005801; C:cis-Golgi network; IEA:Ensembl GO; GO:0005783; C:endoplasmic reticulum; IEA:Ensembl GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW GO; GO:0003700; F:DNA-binding transcription factor activity; TAS:ProtInc InterPro; IPR039775; PHTF1/2 InterPro; IPR021980; TF_homeodomain_male PANTHER; PTHR12680; PTHR12680; 1 Pfam; PF12129; Phtf-FEM1B_bdg; 1 2: Evidence at transcript level; Alternative splicing; DNA-binding; Nucleus; Phosphoprotein; Reference proteome; Transcription; Transcription regulation CHAIN 1..762 /note="Putative homeodomain transcription factor 1" /id="PRO_0000127423" MOD_RES 272 /note="Phosphoserine" /evidence="ECO:0000250|UniProtKB:Q9QZ09" MOD_RES 276 /note="Phosphoserine" /evidence="ECO:0000250|UniProtKB:Q9QZ09" MOD_RES 277 /note="Phosphoserine" /evidence="ECO:0000250|UniProtKB:Q9QZ09" MOD_RES 334 /note="Phosphoserine" /evidence="ECO:0000250|UniProtKB:Q9QZ09" MOD_RES 336 /note="Phosphoserine" /evidence="ECO:0000250|UniProtKB:Q9QZ09" VAR_SEQ 632..637 /note="LQGHKT -> KVSHLL (in isoform 2)" /evidence="ECO:0000303|PubMed:15489334" /id="VSP_002144" VAR_SEQ 638..762 /note="Missing (in isoform 2)" /evidence="ECO:0000303|PubMed:15489334" /id="VSP_002145" CONFLICT 245 /note="W -> C (in Ref. 1; CAB51572)" /evidence="ECO:0000305" CONFLICT 251 /note="A -> P (in Ref. 1; CAB51572)" /evidence="ECO:0000305" CONFLICT 518 /note="C -> G (in Ref. 1; CAB51572)" /evidence="ECO:0000305" CONFLICT 529 /note="L -> W (in Ref. 1; CAB51572)" /evidence="ECO:0000305" CONFLICT 638 /note="F -> S (in Ref. 1; CAB51572)" /evidence="ECO:0000305" SEQUENCE 762 AA; 87252 MW; 0813B7A668262DD9 CRC64; MASNERDAIS WYQKKIGAYD QQIWEKSIEQ TQIKGLKNKP KKMGHIKPDL IDVDLIRGST FAKAKPEIPW TSLTRKGLVR VVFFPLFSNW WIQVTSLRIF VWLLLLYFMQ VIAIVLYLMM PIVNISEVLG PLCLMLLMGT VHCQIVSTQI TRPSGNNGNR RRRKLRKTVN GDGSRENGNN SSDKVRGIET LESVPIIGGF WETIFGNRIK RVKLISNKGT ETDNDPSCVH PIIKRRQCRP EIRMWQTREK AKFSDGEKCR REAFRRLGNG VSDDLSSEED GEARTQMILL RRSVEGASSD NGCEVKNRKS ILSRHLNSQV KKTTTRWCHI VRDSDSLAES EFESAAFSQG SRSGVSGGSR SLNMSRRDSE STRHDSETED MLWDDLLHGP ECRSSVTSDS EGAHVNTLHS GTKRDPKEDV FQQNHLFWLQ NSSPSSDRVS AIIWEGNECK KMDMSVLEIS GIIMSRVNAY QQGVGYQMLG NVVTIGLAFF PFLHRLFREK SLDQLKSISA EEILTLFCGA PPVTPIIVLS IINFFERLCL TWMFFFMMCV AERTYKQRFL FAKLFSHITS ARKARKYEIP HFRLKKVENI KIWLSLRSYL KRRGPQRSVD VVVSSVFLLT LSIAFICCAQ VLQGHKTFLN DAYNWEFLIW ETALLLFLLR LASLGSETNK KYSNVSILLT EQINLYLKME KKPNKKEQLT LVNNVLKLST KLLKELDTPF RLYGLTMNPL IYNITRVVIL SAVSGVISDL LGFNIRLWKI KS
Research Areas
Citations (0)

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PHTF1 may play a role in transcription regulation.


Douroudis,K.,, BMC Med. Genet. 11, 11 (2010)Cooper,J.D.,, Nat. Genet. 40 (12), 1399-1401 (2008)

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$ 277.78
Cat# BP9167c
Availability: 2 weeks
Bulk Size

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