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TPH2 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8IWU9 |
|---|---|
| Clone Names | 90625249 |
| Gene ID | 121278 |
|---|---|
| Other Names | Tryptophan 5-hydroxylase 2, Neuronal tryptophan hydroxylase, Tryptophan 5-monooxygenase 2, TPH2, NTPH |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9177c was selected from the Center region of human TPH2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | TPH2 |
|---|---|
| Synonyms | NTPH |
| Tissue Location | Brain specific. |
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Provided below are standard protocols that you may find useful for product applications.
Background
This protein is a member of the cytidine deaminase gene family. It is one of seven related genes or pseudogenes found in a cluster, thought to result from gene duplication, on chromosome 22. Members of the cluster encode proteins that are structurally and functionally related to the C to U RNA-editing cytidine deaminase APOBEC1. It is thought that the proteins may be RNA editing enzymes and have roles in growth or cell cycle control.
References
Khatua,A.K., et.al., Virology 400 (1), 68-75 (2010)Koning,F.A., et.al., J. Virol. 83 (18), 9474-9485 (2009)
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