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ADH6 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession P28332
Clone Names 80411105
Additional Information
Gene ID 130
Other Names Alcohol dehydrogenase 6, ADH6
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9203c was selected from the Center region of human ADH6. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name ADH6
Function Alcohol dehydrogenase (PubMed:1755855). Catalyzes the NAD- dependent oxidation of primary alcohols to the corresponding aldehydes (PubMed:1755855). Oxidizes secondary alcohols to the corresponding ketones (By similarity).
Cellular Location Cytoplasm.
Tissue Location Stomach and liver..
Research Areas
Citations (0)
citation

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Background

ADH6 encodes class V alcohol dehydrogenase, which is a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. This protein is expressed in the stomach as well as in the liver, and it contains a glucocorticoid response element upstream of its 5' UTR, which is a steroid hormone receptor binding site.

References

Cui,R., et.al., Gastroenterology 137 (5), 1768-1775 (2009)Saito,A., et.al., J. Hum. Genet. 54 (6), 317-323 (2009)Tabakoff,B., et.al., BMC Biol. 7, 70 (2009)

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$ 277.78
Cat# BP9203c
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