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NIPA2 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q8N8Q9 |
|---|---|
| Clone Names | 91109114 |
| Gene ID | 81614 |
|---|---|
| Other Names | Magnesium transporter NIPA2, Non-imprinted in Prader-Willi/Angelman syndrome region protein 2, NIPA2 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9204b was selected from the C-term region of human NIPA2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NIPA2 |
|---|---|
| Function | Acts as a selective Mg(2+) transporter. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. Early endosome {ECO:0000250|UniProtKB:Q9JJC8}. Note=Recruited to the cell membrane in response to low extracellular magnesium {ECO:0000250|UniProtKB:Q9JJC8} |
| Tissue Location | Widely expressed.. |
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Provided below are standard protocols that you may find useful for product applications.
Background
NIPA2 belongs to the NIPA family. It is a multi-pass membrane protein. The function of the NIPA2 protein remains unknown.
References
Bittel,D.C., et.al., Pediatrics 118 (4), E1276-E1283 (2006)Lefevre,C., et.al, Hum. Mol. Genet. 13 (20), 2473-2482 (2004)Glinsky,G.V., et.al, J. Clin. Invest. 113 (6), 913-923 (2004)
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