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FMOD Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q06828
Clone Names 91009114
Additional Information
Gene ID 2331
Other Names Fibromodulin, FM, Collagen-binding 59 kDa protein, Keratan sulfate proteoglycan fibromodulin, KSPG fibromodulin, FMOD, FM, SLRR2E
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9243b was selected from the C-term region of human FMOD. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name FMOD
Synonyms FM, SLRR2E
Function Affects the rate of fibrils formation. May have a primary role in collagen fibrillogenesis (By similarity).
Cellular Location Secreted, extracellular space, extracellular matrix
Research Areas
Citations (0)
citation

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Background

Fibromodulin is a member of a family of small interstitial proteoglycans, containing a central region composed of leucine-rich repeats with 4 keratan sulfate chains flanked by disulfide-bonded terminal domains. It may participate in the assembly of the extracellular matrix as it interacts with type I and type II collagen fibrils and inhibits fibrillogenesis in vitro. It may also regulate TGF-beta activities by sequestering TGF-beta into the extracellular matrix.

References

Ehret,G.B., et.al, Eur. J. Hum. Genet. 17 (12), 1650-1657 (2009)Tillgren,V., et.al, J. Biol. Chem. 284 (42), 28543-28553 (2009)

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$ 277.78
Cat# BP9243b
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