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TMTC2 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q8N394
Clone Names 91109086
Additional Information
Gene ID 160335
Other Names Transmembrane and TPR repeat-containing protein 2, TMTC2
Target/Specificity The synthetic peptide sequence used to generate the antibody AP9252b was selected from the C-term region of human TMTC2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TMTC2 (HGNC:25440)
Function Transfers mannosyl residues to the hydroxyl group of serine or threonine residues. The 4 members of the TMTC family are O-mannosyl- transferases dedicated primarily to the cadherin superfamily, each member seems to have a distinct role in decorating the cadherin domains with O-linked mannose glycans at specific regions. Also acts as O- mannosyl-transferase on other proteins such as PDIA3.
Cellular Location Membrane; Multi-pass membrane protein. Endoplasmic reticulum
Research Areas
Citations (0)
citation

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References

Nakano,M., et.al, Proc. Natl. Acad. Sci. U.S.A. 106 (31), 12838-12842 (2009)Mole,D.R., et.al, J. Biol. Chem. 284 (25), 16767-16775 (2009)

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$ 277.78
Cat# BP9252b
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