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NPY5R Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q15761 |
|---|---|
| Clone Names | 90723095 |
| Gene ID | 4889 |
|---|---|
| Other Names | Neuropeptide Y receptor type 5, NPY5-R, NPY-Y5 receptor, NPYY5-R, Y5 receptor, NPY5R, NPYR5 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9265c was selected from the Center region of human NPY5R. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | NPY5R |
|---|---|
| Synonyms | NPYR5 |
| Function | Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be associated with food intake. Could be involved in feeding disorders. |
| Cellular Location | Cell membrane; Multi-pass membrane protein. |
| Tissue Location | Brain; hypothalamus. |
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Provided below are standard protocols that you may find useful for product applications.
Background
NPY5R is receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. NPY5R seems to be associated with food intake. This protein could be involved in feeding disorders.
References
Gratacos,M., et.al, Am. J. Med. Genet. B Neuropsychiatr. Genet. 150B (6), 808-816 (2009)Arnett,D.K., et.al, J. Hypertens. 27 (8), 1585-1593 (2009)Umeda,T., et.al, Peptides 30 (8), 1441-1447 (2009)
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