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ARGLU1 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NWB6 |
|---|---|
| Clone Names | 90819146 |
| Gene ID | 55082 |
|---|---|
| Other Names | Arginine and glutamate-rich protein 1, ARGLU1 |
| Target/Specificity | The synthetic peptide sequence used to generate the antibody AP9290a was selected from the N-term region of human ARGLU1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay. |
| Format | Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ARGLU1 |
|---|---|
| Function | Required for the estrogen-dependent expression of ESR1 target genes. Can act in cooperation with MED1. |
| Cellular Location | Nucleus. Note=Recruited, in an estrogen-dependent manner, to ESR1 target gene promoters. Colocalizes with MED1 |
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Provided below are standard protocols that you may find useful for product applications.
Background
ARGLU1 belongs to the UPF0430 family. There are two named isoforms.
References
Olsen,J.V., et.al, Cell 127 (3), 635-648 (2006)Beausoleil,S.A., et.al., Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)Beausoleil,S.A., et.al, Proc. Natl. Acad. Sci. U.S.A. 101 (33), 12130-12135 (2004)
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