ENTPD2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9Y5L3 |
|---|
| Gene ID | 954 |
|---|---|
| Other Names | Ectonucleoside triphosphate diphosphohydrolase 2, NTPDase 2, 361-, CD39 antigen-like 1, Ecto-ATP diphosphohydrolase 2, Ecto-ATPDase 2, Ecto-ATPase 2, ENTPD2, CD39L1 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ENTPD2 |
|---|---|
| Synonyms | CD39L1 |
| Function | In the nervous system, could hydrolyze ATP and other nucleotides to regulate purinergic neurotransmission. Hydrolyzes ADP only to a marginal extent. The order of activity with different substrates is ATP > GTP > CTP = ITP > UTP >> ADP = UDP. |
| Cellular Location | [Isoform Long]: Cell membrane; Multi-pass membrane protein [Isoform gamma]: Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Tissue Location | Brain, placenta, skeletal muscle, kidney, pancreas, heart, ovary, testis, colon, small intestine, prostate and pancreas. No expression in adult thymus, spleen, lung, liver and peripheral blood leukocytes |

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Provided below are standard protocols that you may find useful for product applications.
Background
ENTPD2 is the type 2 enzyme of the ecto-nucleoside triphosphate diphosphohydrolase family (E-NTPDase). E-NTPDases are a family of ecto-nucleosidases that hydrolyze 5'-triphosphates. This ecto-ATPase is an integral membrane protein.
References
Chiang,W.C. Biochemistry 47 (33), 8775-8785 (2008)Javed,R. Biochemistry 46 (22), 6617-6627 (2007)Mukasa,T.Biochemistry 44 (33), 11160-11170 (2005)
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