GPR135 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | Q8IZ08 |
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Gene ID | 64582 |
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Other Names | Probable G-protein coupled receptor 135, GPR135 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | GPR135 |
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Function | Orphan receptor. Has spontaneous activity for beta-arrestin recruitment (PubMed:28827538). Shows a reciprocal regulatory interaction with the melatonin receptor MTNR1B most likely through receptor heteromerization (PubMed:28827538). |
Cellular Location | Cell membrane; Multi-pass membrane protein. Endosome membrane; Multi-pass membrane protein. Note=Colocalizes with ARRB2/beta-arrestin-2 in the endosome. |
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Provided below are standard protocols that you may find useful for product applications.
Background
GPR135 is an orphan receptor belonging to the G-protein coupled receptor 1 family.
References
Yoshida,T. Int. J. Mol. Med. 25 (4), 649-656 (2010)Fredriksson,R. FEBS Lett. 554 (3), 381-388 (2003)Vassilatis,D.K. Proc. Natl. Acad. Sci. U.S.A. 100 (8), 4903-4908 (2003)
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