|Other Names||Galactose-3-O-sulfotransferase 4, Gal3ST-4, 282-, Beta-galactose-3-O-sulfotransferase 4, Gal-beta-1, 3-GalNAc 3'-sulfotransferase, GAL3ST4|
|Format||Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.|
|Storage||Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.|
|Precautions||This product is for research use only. Not for use in diagnostic or therapeutic procedures.|
|Function||Catalyzes the transfer of sulfate to beta-1,3-linked galactose residues in O-linked glycoproteins. Good substrates include asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta- 1,6)GalNAc.|
|Cellular Location||Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein|
|Tissue Location||Expressed mainly in placenta, thymus, testis, ovary, spinal cord, trachea and adrenal gland and at low levels in brain, lung, spleen, prostate, small intestine, colon, stomach thyroid and lymph node.|
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Provided below are standard protocols that you may find useful for product applications.
GAL3ST4 encodes a member of the galactose-3-O-sulfotransferase protein family. The product of this gene catalyzes sulfonation by transferring a sulfate to the C-3' position of galactose residues in O-linked glycoproteins. This enzyme is highly specific for core 1 structures, with asialofetuin, Gal-beta-1,3-GalNAc and Gal-beta-1,3 (GlcNAc-beta-1,6)GalNAc being good substrates.
Wan,D. Proc. Natl. Acad. Sci. U.S.A. 101 (44), 15724-15729 (2004)Chandrasekaran,E.V. J. Biol. Chem. 279 (11), 10032-10041 (2004)Seko,A. J. Biol. Chem. 276 (28), 25697-25704 (2001)
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