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ND2 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P03891 |
|---|
| Gene ID | 4536 |
|---|---|
| Other Names | NADH-ubiquinone oxidoreductase chain 2, NADH dehydrogenase subunit 2, MT-ND2, MTND2, NADH2, ND2 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | MT-ND2 (HGNC:7456) |
|---|---|
| Synonyms | MTND2, NADH2, ND2 |
| Function | Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) which catalyzes electron transfer from NADH through the respiratory chain, using ubiquinone as an electron acceptor (PubMed:16996290). Essential for the catalytic activity and assembly of complex I (PubMed:16996290). |
| Cellular Location | Mitochondrion inner membrane {ECO:0000250|UniProtKB:P03892}; Multi-pass membrane protein |
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Provided below are standard protocols that you may find useful for product applications.
Background
ND2 is core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. This protein complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
References
Saitoh,K., et.al., J. Mol. Evol. 63 (6), 826-841 (2006)
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