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TSPAN33 Antibody (C-term) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q86UF1
Additional Information
Gene ID 340348
Other Names Tetraspanin-33, Tspan-33, Penumbra, hPen, Proerythroblast new membrane, TSPAN33, PEN
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name TSPAN33
Synonyms PEN
Function Plays an important role in normal erythropoiesis (By similarity). It has a role in the differentiation of erythroid progenitors (By similarity). Regulates maturation and trafficking of the transmembrane metalloprotease ADAM10 (PubMed:26686862, PubMed:30463011). Negatively regulates ligand-induced Notch activity probably by regulating ADAM10 activity (PubMed:26686862). Mediates docking of ADAM10 to zonula adherens by interacting with ADAM10 and, in a PDZD11-dependent manner, with the zonula adherens protein PLEKHA7 (PubMed:30463011).
Cellular Location Cell membrane; Multi-pass membrane protein. Cell junction, adherens junction. Cytoplasm. Note=Is localized to zonula adherens by PLEKHA7 by a PDZD11-dependent interaction
Tissue Location Predominantly expressed in erythroblasts.
Research Areas
Citations (0)

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Background

TSPAN33 plays an important role in normal erythropoiesis. It has a role in the differentiation of erythroid progenitors.

References

Heikens, M.J., et al. Blood 109(8):3244-3252(2007)Huang, S., et al. Genomics 86(6):674-684(2005)Chen, Z., et al. Cancer Genet. Cytogenet. 162(2):95-98(2005)

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$ 277.78
Cat# BP9397b
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