Foundational characteristics of cancer include proliferation, angiogenesis, migration, evasion of apoptosis, and cellular immortality. Find key markers for these cellular processes and antibodies to detect them.
The SUMOplot™ Analysis Program predicts and scores sumoylation sites in your protein. SUMOylation is a post-translational modification involved in various cellular processes, such as nuclear-cytosolic transport, transcriptional regulation, apoptosis, protein stability, response to stress, and progression through the cell cycle.
The Autophagy Receptor Motif Plotter predicts and scores autophagy receptor binding sites in your protein. Identifying proteins connected to this pathway is critical to understanding the role of autophagy in physiological as well as pathological processes such as development, differentiation, neurodegenerative diseases, stress, infection, and cancer.
ANO7 Antibody (N-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q6IWH7 |
|---|
| Gene ID | 50636 |
|---|---|
| Other Names | Anoctamin-7, Dresden transmembrane protein of the prostate, D-TMPP, IPCA-5, New gene expressed in prostate, Prostate cancer-associated protein 5, Transmembrane protein 16G, ANO7, NGEP, PCANAP5, TMEM16G |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | ANO7 |
|---|---|
| Synonyms | NGEP, PCANAP5, TMEM16G |
| Function | Has calcium-dependent phospholipid scramblase activity; scrambles phosphatidylserine, phosphatidylcholine and galactosylceramide (By similarity). Does not exhibit calcium-activated chloride channel (CaCC) activity (PubMed:22075693). May play a role in cell-cell interactions (PubMed:17308099). |
| Cellular Location | [Isoform 1]: Cell membrane; Multi-pass membrane protein. Cell junction. Endoplasmic reticulum. Note=Concentrates at sites of cell-cell contact (PubMed:17308099). Shows an intracellular localization according to PubMed:22075693 and PubMed:20056604 |
| Tissue Location | Specifically expressed in epithelial cells of the prostate (at protein level). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
info@abcepta.com, and receive a free "I Love Antibodies" mug.
Provided below are standard protocols that you may find useful for product applications.
Background
ANO7 may act as a calcium-activated chloride channel. This protein May play a role in cell-cell interactions.
References
Cereda, V., et al. Cancer Immunol. Immunother. 59(1):63-71(2010)Hartzell, H.C., et al. J. Physiol. (Lond.) 587 (PT 10), 2127-2139 (2009) Das, S., et al. Cancer Res. 68(15):6306-6312(2008)Kiessling, A., et al. Prostate 64(4):387-400(2005)Katoh, M., et al. Int. J. Mol. Med. 14(4):759-764(2004)
If you have used an Abcepta product and would like to share how it has performed, please click on the "Submit Review" button and provide the requested information. Our staff will examine and post your review and contact you if needed.
If you have any additional inquiries please email technical services at tech@abcepta.com.
Ordering Information
Other Products
Shipping Information
