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MAFA Antibody (Center) Blocking Peptide

Synthetic peptide

Product Information
Primary Accession Q8NHW3
Additional Information
Gene ID 389692
Other Names Transcription factor MafA, Pancreatic beta-cell-specific transcriptional activator, Transcription factor RIPE3b1, V-maf musculoaponeurotic fibrosarcoma oncogene homolog A, MAFA
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Function Transcription factor that activates insulin gene expression (PubMed:15993959, PubMed:12011435). Acts synergistically with NEUROD1/BETA2 and PDX1 (PubMed:15993959). Binds the insulin enhancer C1/RIPE3b element (PubMed:12011435). Binds to consensus TRE-type MARE 5'-TGCTGACTCAGCA-3' DNA sequence (PubMed:23148532, PubMed:29339498).
Cellular Location Nucleus {ECO:0000255|PROSITE-ProRule:PRU00978, ECO:0000269|PubMed:12011435, ECO:0000269|PubMed:12917329}
Tissue Location Expressed in the islets of Langerhans (at protein level).
Research Areas
Citations (0)

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MAFA is a transcription factor that binds RIPE3b, a conserved enhancer element that regulates pancreatic beta cell-specific expression of the insulin gene.


Kondo, T., et al. Mol. Endocrinol. 23(8):1281-1290(2009)Kaneto, H., et al. Adv. Drug Deliv. Rev. 61 (7-8), 489-496 (2009) Garin, I., et al. Diabet. Med. 26(7):746-748(2009)Vanderford, N.L., et al. Arch. Biochem. Biophys. 480(2):138-142(2008)Martin, C.C., et al. J. Mol. Endocrinol. 41(5):315-328(2008)

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$ 277.78
Cat# BP9440c
Availability: 2 weeks
Bulk Size

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