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GPATCH3 Antibody (Center) Blocking Peptide

Synthetic peptide

     
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Product Information
Primary Accession Q96I76
Additional Information
Gene ID 63906
Other Names G patch domain-containing protein 3, GPATCH3, GPATC3
Format Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
StorageMaintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C.
PrecautionsThis product is for research use only. Not for use in diagnostic or therapeutic procedures.
Protein Information
Name GPATCH3
Synonyms GPATC3
Function Involved in transcriptional regulation. It is able to activate transcription from the CXCR4 promoter and therefore it might control neural crest cell migration involved in ocular and craniofacial development (PubMed:28397860). Is a negative regulator of immune antiviral response, acting via down-regulation of RIG-I-like receptors signaling and inhibition of type I interferon production. The control mechanism involves interaction with mitochondrial MAVS and inhibition of MAVS assembly with downstream proteins implicated in antiviral response, such as TBK1 and TRAF6 (PubMed:28414768).
Cellular Location Nucleus. Cytoplasm
Tissue Location Expressed in ocular tissues including retinal pigment epithelium, cornea, ciliary muscle and non-pigmented ciliary epithelium. Also expressed in optic nerve, cartilage, skin and lymph node.
Research Areas
Citations (0)

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References

Gregory, S.G., et al. Nature 441(7091):315-321(2006)

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$ 277.78
Cat# BP9498c
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