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C9orf78 Antibody (C-term) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | Q9NZ63 |
|---|
| Gene ID | 51759 |
|---|---|
| Other Names | Uncharacterized protein C9orf78, Hepatocellular carcinoma-associated antigen 59, C9orf78, HCA59 |
| Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
| Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
| Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
| Name | C9orf78 |
|---|---|
| Synonyms | HCA59 {ECO:0000303|PubMed:12097419} |
| Function | Plays a role in pre-mRNA splicing by promoting usage of the upstream 3'-splice site at alternative NAGNAG splice sites; these are sites featuring alternative acceptor motifs separated by only a few nucleotides (PubMed:35241646). May also modulate exon inclusion events (PubMed:35241646). Plays a role in spliceosomal remodeling by displacing WBP4 from SNRNP200 and may act to inhibit SNRNP200 helicase activity (PubMed:35241646). Binds U5 snRNA (PubMed:35241646). Required for proper chromosome segregation (PubMed:35167828). Not required for splicing of shelterin components (PubMed:35167828). |
| Cellular Location | Nucleus. Chromosome, centromere. Note=Dispersed throughout the nucleus during interphase (PubMed:35167828). Colocalizes with microtubule attachment sites at centromeres following mitotic checkpoint activation (PubMed:35167828). |
Thousands of laboratories across the world have published research that depended on the performance of antibodies from Abcepta to advance their research. Check out links to articles that cite our products in major peer-reviewed journals, organized by research category.
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Provided below are standard protocols that you may find useful for product applications.
References
??ugiyama, N., et al. Mol. Cell Proteomics 6(6):1103-1109(2007)??lsen, J.V., et al. Cell 127(3):635-648(2006)??lsen, J.V., et al. Cell 127(3):635-648(2006)??ush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)??ush, J., et al. Nat. Biotechnol. 23(1):94-101(2005)
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