AMPD1 Antibody (Center) Blocking Peptide
Synthetic peptide
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
Primary Accession | P23109 |
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Gene ID | 270 |
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Other Names | AMP deaminase 1, AMP deaminase isoform M, Myoadenylate deaminase, AMPD1 |
Format | Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed. |
Storage | Maintain refrigerated at 2-8°C for up to 6 months. For long term storage store at -20°C. |
Precautions | This product is for research use only. Not for use in diagnostic or therapeutic procedures. |
Name | AMPD1 (HGNC:468) |
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Function | AMP deaminase plays a critical role in energy metabolism. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Adenosine monophosphate deaminase 1 catalyzes the deamination of AMP to IMP in skeletal muscle and plays an important role in the purine nucleotide cycle. Two other genes have been identified, AMPD2 and AMPD3, for the liver- and erythocyte-specific isoforms, respectively. Deficiency of the muscle-specific enzyme is apparently a common cause of exercise-induced myopathy and probably the most common cause of metabolic myopathy in the human.
References
McGeachie, M., et al. Circulation 120(24):2448-2454(2009)Hanisch, F., et al. J. Neurol. 255(3):318-322(2008)Vladutiu, G.D., et al. Muscle Nerve 34(2):153-162(2006)Mahnke-Zizelman, D.K., et al. J. Biol. Chem. 277(45):42654-42662(2002)
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