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Elcatonin recombinant protein
Elcatonin, 60731-46-6
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Other Names | Elcatonin, 60731-46-6 |
|---|---|
| Source | Synthetic |
| Assay&Purity | SDS-PAGE; ≥94% |
| Assay2&Purity2 | HPLC; ≥94% |
| Recombinant | No |
| Target/Specificity | Elcatonin |
| Application Notes | Centrifuge the vial prior to opening. Reconstitute in sterile dW to a concentration ≥ 100 µg/ml. This solution can then be diluted into other aqueous buffers and stored at 4 °C for 2-7 days and at -20 °C for future use. |
| Format | Lyophilized |
| Storage | -20°C; Sterile filtered and lyophilized with no additives |
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Provided below are standard protocols that you may find useful for product applications.
Background
Elcatonin is a Calcitonin derivative which is transformed from eel´s calcitonin by changing the S-S bond into the stable C-N bond. It inhibits the absorption and autolysis of bones, thus leads to blood calcium descending. In addition, it inhibits the bone salts dissolving and transferring and promotes the excretion of calcium and phosphorus in urine. Meanwhile, it inhibits renal tubules reabsorbing calcium, phosphorus and sodium and keeps blood calcium at normal level. It is mainly used for remitting or eliminating the pain caused by Osteoporosis. Elcatonin synthetic is a single, non-glycosylated polypeptide chain containing 31 amino acids.
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