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FGF-8, human recombinant protein
Fibroblast Growth Factor-8, FGF-8b, AIGF, HBGF
- SPECIFICATION
- CITATIONS
- PROTOCOLS
- BACKGROUND
| Primary Accession | P55075 |
|---|---|
| Calculated MW | 22.4 kDa |
| Gene ID | 2253 |
|---|---|
| Gene Symbol | FGF-8 |
| Other Names | Fibroblast Growth Factor-8, FGF-8b, AIGF, HBGF, Androgen-induced growth factor, Heparin-binding growth factor 8 |
| Gene Source | Human |
| Source | E. coli |
| Assay&Purity | SDS-PAGE; ≥95% |
| Assay2&Purity2 | HPLC; |
| Recombinant | Yes |
| Results | <0.5 ng/ml |
| Target/Specificity | FGF-8 |
| Application Notes | Centrifuge the vial prior to opening. Reconstitute in 5 mM Tris, pH 8.0 to a concentration of 0.1-1 mg/ml. This solution can be diluted into other aqueous buffers and stored at 4°C for 1 week or -20°C for future use. Repeated freeze/thaw cycles will result in some loss of activity. |
| Format | Lyophilized protein |
| Storage | -20°C; Lyophilized in 10 mM Tris, pH 8.0 + 75 mM NaCl. The protein may appear as a haze or film, which may not be seen at the bottom of the vial. |
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Provided below are standard protocols that you may find useful for product applications.
Background
Fibroblast Growth Factor-8 (FGF-8) is also known as Androgen-induced Growth Factor (AIGF), a heparin binding growth factor, which stimulates the proliferation and activation of cells that express the FGF receptors. Recombinant human FGF-8 is a 22.4 kDa protein containing 193 amino acid residues.
References
Tanaka A.,et al.FEBS Lett. 363:226-230(1995).
Ghosh A.K.,et al.Cell Growth Differ. 7:1425-1434(1996).
Gemel J.,et al.Genomics 35:253-257(1996).
Payson R.A.,et al.Oncogene 13:47-53(1996).
Tanaka S.,et al.Dig. Dis. Sci. 46:1016-1021(2001).
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